Colds itchy throat, cough mainly due to viral infection caused by pharyngeal mucosal congestion and edema or inflammatory mediators caused by hypersensitivity reaction related. Colds are acute upper respiratory tract infectious diseases caused by viral invasion. Virus replication and proliferation in the respiratory mucosa, can cause pharyngeal mucosal congestion, edema, caused by local mucosal secretion increase, followed by itchy throat, cough and other symptoms. In addition, symptoms such as itchy throat and cough may also be related to virus-induced inflammatory mediators leading to upper respiratory tract afferent nerve hypersensitivity. During cold and flu, it is recommended to take more rest and drink more warm water to improve the symptoms of throat discomfort and cough. If the symptoms are severe, cold and flu medications such as cotrimoxazole can be given to treat the symptoms. Itchy throat and cough can also be caused by other diseases. If the symptoms are not relieved or aggravated, it is recommended to consult a doctor for a clear diagnosis and standardized treatment under the doctor’s guidance.