Platelet 48 is more serious, and possible diseases include systemic lupus erythematosus, dry syndrome, and thrombocytopenic purpura. 1. Systemic lupus erythematosus: hemolytic anemia may occur, and white blood cells and platelets will decrease. Early symptoms of SLE are fever, arthralgia, butterfly-shaped erythema on the face, etc. If left untreated, it can cause systemic multi-system and multi-organ damage, functional failure, and ultimately lead to death. 2. Dry syndrome: 13% of patients will have thrombocytopenia. Dry syndrome often causes dry eyes and mouth, belongs to autoimmune disease, cannot be cured, the prognosis is generally better, but untimely treatment can be life-threatening. 3. Thrombocytopenic purpura: Thrombocytopenia. It can cause skin bleeding (e.g. petechiae, ecchymosis), oral and nasal bleeding (e.g. bleeding gums, nosebleeds), gastrointestinal bleeding (e.g. vomiting blood, black stools), etc. In severe cases, intracranial bleeding can occur. In severe cases, intracranial hemorrhage can occur, leading to death. In addition to the above diseases, thrombocytopenia can also be seen in leukemia, etc. If the above test results occur, it is recommended to go to the hospital to find out the cause of the disease and give targeted treatment under the guidance of the doctor to avoid adverse effects.