The causes of inguinal lymph node enlargement include: infection, anti-infection treatment; hematologic diseases, surgery and chemotherapy treatment; lymphatic metastasis of malignant tumors, treatment of primary tumors, removal of lymph nodes; immune system disorders and other disorders lead to. 1. Infections: including bacterial, viral, Mycobacterium tuberculosis, syphilis, parasitic infections and so on. Bacterial infections, need cephalosporin antibacterial drug treatment; viral infections, you can acyclovir and other antiviral drugs; lymphatic tuberculosis, need rifampicin, isoniazid and other anti-tuberculosis treatment; syphilis, penicillin antibacterial drug treatment and so on. 2. Blood system diseases: for example, lymphoma, first surgical removal of enlarged lymph nodes, according to the nature of the tumor, using chemotherapy, targeted drug therapy. For leukemia, chemotherapy drugs and bone marrow transplantation are needed. 3. Immune system diseases: systemic lupus erythematosus, need to use immunosuppressants, such as tacrolimus; oral glucocorticoid drugs, such as methylprednisolone and so on. Inguinal lymph node enlargement is also seen in other causes, it is recommended to consult a doctor in a timely manner, under the guidance of a professional doctor to standardize the treatment and medication, so as not to delay the condition.