Spironolactone can treat high blood pressure, but it is not a complete cure. Spironolactone has a diuretic effect and is one of the 5 basic medications used to treat high blood pressure. The diuretic effect is able to reduce blood volume and lower the tone of peripheral blood vessels, which can be extremely effective. Spironolactone is also able to inhibit the aldosterone level in the body and reduce the effect of cholesterol-induced increase in blood pressure, which can be used for hypertension caused by aldosteronism. Spironolactone can treat both primary and secondary hypertension, but there is no cure for hypertension, only symptom control. Adverse reactions of spironolactone include thirst, fatigue, nausea, male breast development, female breast distension, etc. It is contraindicated for patients who are allergic to the drug components and hyperkalemia. Clinical oral spironolactone in the treatment of hypertension, the drug should be used under the guidance of a physician.