Irbesartan hydrochlorothiazide tablets and levamlodipine can be taken at the same time, is a common combination of high blood pressure medication program, should be used under the guidance of a doctor. Irbesartan hydrochlorothiazide tablets is a compound preparation, Irbesartan belongs to the angiotensin 2 receptor antagonist (ARB), can block the angiotensin vasoconstriction, aldosterone secretion; hydrochlorothiazide is a diuretic, which can increase the excretion of sodium and chloride. Irbesartan hydrochlorothiazide tablets should not be used in pregnant women from 4 to 9 months and lactating women, patients with severe renal impairment, hypokalemia, etc. Adverse reactions such as dizziness, nausea, vomiting and abnormal urination may occur. Levamlodipine is a dihydropyridine calcium channel antagonist antihypertensive drug (CCB). It should not be used in persons with a history of hypersensitivity to this drug and should be used with caution in patients with liver injury. Adverse reactions such as headache, edema, fatigue and insomnia may occur after use. Irbesartan hydrochlorothiazide tablets and levamlodipine can be used in combination, and the synergy of the two can enhance the efficacy, in line with the three-drug combination regimen of hypertension ARB + dihydropyridine CCB + thiazide diuretics. It should be used under the guidance of a doctor, do not arbitrarily add drugs or adjust the dose to avoid the occurrence of adverse reactions.