Esophageal dentate line and barrett’s esophagus are two concepts respectively: esophageal dentate line is the normal tissue structure at the junction of esophagus and stomach; barrett’s esophagus is the pathological tissue structure in which the normal squamous epithelial cells of esophagus metamorphose into columnar epithelial cells. 1. esophageal dentate line: normal esophageal mucosal folds gather with each other when they pass through the diaphragmatic esophageal hiatus, gradually separate after passing through, and connect with the longitudinal folds of the gastric cardia and the gastric lesser curvature in a radial state; on upper gastrointestinal tractography, the junction between the gastric mucosa and the esophagus presents a jagged shape, i.e., the esophageal dentate line. 2. Barrett’s esophagus: Barrett’s esophagus can be diagnosed when the squamous epithelial cells of the mucosa several centimeters above the dentate line of the esophagus degenerate into a single layer of columnar epithelial cells. Most of the barrett’s esophagus is caused by gastroesophageal reflux disease (GERD), and the reddish-orange irregular lesions are visible to the naked eye at the mucous membrane, which can be secondary to ulcers, esophageal stenosis, and so on. Barrett’s esophagus is a precancerous lesion, but the cancer rate is very low. In daily life, we should pay attention to the dietary rules and eat less spicy and stimulating food; if lesions are found, we need to go to regular hospitals for regular follow-up and early treatment.