The cowpox vaccine protects against the monkeypox virus to some extent, but is not 100% effective. Cowpox is a vaccine prepared from the cowpox virus for the prevention of smallpox. Cowpox virus is a virus that causes mild cowpox lesions in cattle. Since cowpox virus has the same antigenic properties as smallpox virus, a person who receives cowpox vaccine can also acquire immunity against smallpox virus at the same time. Since monkeypox virus and cowpox virus also have cross-antigen, it is also possible to prevent monkeypox through cowpox vaccination. However, the effectiveness rate of the vaccination is not 100%, with some studies indicating an effectiveness rate of about 85%. Cowpox vaccination needs to be administered at designated vaccination centers by professional health care workers.