Primary biliary cholangitis is usually not completely cured and requires long-term maintenance therapy. Primary biliary cholangitis, also known as primary biliary cirrhosis, is an organ-specific chronic cholestatic autoimmune liver disease. If early can be diagnosed in time, under the guidance of the doctor to choose the appropriate drugs standardized treatment, most of the patients do not develop into cirrhosis, and standardized treatment, the efficacy of the patients, life expectancy is the same as a healthy person, but still need to be under the guidance of the doctor to take long-term medication to maintain the effectiveness of the treatment. If the development of the disease is relatively late, ascites, portal hypertension, esophageal varices and other symptoms, actively cooperate with the doctor to do the relevant treatment can only extend the patient’s life expectancy, so primary biliary cholangitis can not achieve the effect of a complete cure. If primary biliary cholangitis occurs, it is recommended to actively cooperate with the doctor to improve the efficacy of medication in sufficient quantity and course.