Crescent body is a kind of renal pathological changes, mainly seen in acute progressive glomerulonephritis. Crescent body is a kind of renal pathological changes, mainly located in the renal capsule, divided into two kinds of cellular crescent and fibrous crescent, mainly seen in acute glomerulonephritis, other nephritis, such as IgA nephropathy can also be found in small quantities. Generally, the presence of crescent often indicates that the renal pathology is relatively more serious, and patients may be treated with a combination of glucocorticoid (prednisone acetate) and immunologic agent (cyclophosphamide), and even plasma exchange and other intensive treatment if necessary. Among them, cellular crescent may recover after active treatment, while fibrous crescent suggests chronicity of the disease, which generally cannot be completely cured. The presence of crescent in renal puncture requires timely consultation in regular hospitals, and the doctor will formulate a reasonable plan according to the pathology and clinical manifestations.