The reference range of CA125 serum test under normal circumstances is <35U/ml, so CA125 reaching 900U/ml in early pregnancy is more serious. CA125 is a tumor marker, is currently the world's most widely used ovarian epithelial tumor markers, in the clinic is widely used in the differential diagnosis of pelvic masses, monitoring the progress of the disease after treatment, and prognosis, especially for the monitoring of the efficacy of quite sensitive. The value of CA125 during pregnancy is 900U/ml which is far more than the normal value, suggesting the possibility of malignant tumors. It is recommended to consult a doctor in time to clarify the specific diagnosis under the doctor's guidance and give targeted treatment.