Tightness and hardness of the stomach in the 6th month of pregnancy often suggests contractions, and it is necessary to determine whether they are pathological or physiological contractions, if they are pathological, they usually need to be treated with fertility preservation. Physiological contractions begin to appear after about 12 weeks of pregnancy, the frequency of contractions is low, the intensity is not great, pregnant women usually do not have pain, only conscious abdominal tightness and hardness, each contraction lasts a short period of time, this kind of contraction can be relieved after appropriate rest, generally do not need special treatment. Pathological contractions are more obvious in frequency and intensity as well as duration than physiological contractions, and pregnant women may feel pain, and these contractions may cause the cervix to become shorter or even dilate the cervix, so it is often necessary to give ritodrine hydrochloride to inhibit contraction treatment in the sixth month of pregnancy. Patients who experience tightening and hardening of the stomach in the 6th month of pregnancy should seek prompt medical attention and follow the doctor’s instructions.