Archie, also known as Azithromycin, can be taken both in the morning and at night, usually without any special requirements. Azithromycin is a commonly used antibiotic, commonly used in the treatment of acute pharyngitis and tonsillitis caused by bacterial infections, otitis media due to sensitive bacterial infections, acute bronchitis and so on. Azithromycin is available in a variety of dosage forms, such as tablets, granules, capsules, dispersible tablets, soft gelatin capsules and so on. Regardless of the dosage form of Azithromycin, there is no special requirement to take it in the morning or at night, and it is usually considered acceptable to take it in the morning or at night. Azithromycin is recommended to be taken on an empty stomach, preferably 1 hour before or 2 hours after a meal, which is conducive to achieving the best absorption efficiency of the drug. It can therefore be taken in the morning before eating, or in the evening 2 hours after dinner. Adverse effects of taking Azithromycin are mainly gastrointestinal discomfort, such as nausea and diarrhea. Contraindications to taking Azithromycin include allergy to macrolide antibiotics, liver and kidney insufficiency should be contraindicated. The specific time of taking the drug, can consult the professional physician’s opinion.