Differential diagnosis of stress and postural hyperhidrosis

       Pressure and postural hyperhidrosis is the sweating response to pressure on one side of the body during position changes and lateral recumbency. It is a manifestation of hyperhidrosis. Hyperhidrosis is a disorder in which excessive sweat gland secretion is caused by sympathetic hyperexcitation. The sympathetic nerve governs sweating throughout the body. Under normal circumstances, the sympathetic nerve regulates body temperature by controlling sweating and heat dissipation. In hyperhidrosis, however, sweating and facial flushing are completely out of control. The excessive sweating and facial flushing leave the patient in a daily state of helplessness, agitation or panic. What are the symptoms that can be confused with them?  Hyperhidrosis can be broadly classified into three categories in terms of its onset. One is due to systemic diseases such as endocrine disorders (hyperthyroidism, diabetes, hyperpituitarism, etc.), neurological diseases, some infectious diseases (malaria, tuberculosis, etc.) and weakness due to long-term illness. As soon as these systemic diseases are controlled the excessive sweating can be resolved. The second is psychogenic sweating, caused by high tension and emotional excitement, is due to sympathetic dysregulation, and the internal use of some sedative drugs (such as atropine, probenecid, belladonna combination, etc.) has a temporary effect, but has side effects such as dry mouth. The third is gustatory sweating, which is another physiological phenomenon, such as excessive sweating caused by eating certain irritating foods (chili, garlic, ginger, cocoa, coffee), a condition that generally does not need to be treated and only requires abstinence from eating.  Generalized hyperhidrosis can be an abnormal physiological reaction or one of the symptoms of certain diseases such as hyperthyroidism and diabetes. Localized hyperhidrosis can be due to sympathetic nerve damage or an abnormal response with increased secretion of choline acetate, resulting in excessive sweat secretion from the small sweat glands. This disorder is characterized by outstanding features, very well diagnosed and difficult to confuse with other diseases. The main difference is the etiology of secondary hyperhidrosis, which should be judged based on the different clinical manifestations. If diabetes mellitus has abnormalities in blood glucose and urine glucose tests, localizing symptoms and signs should be present in organic brain lesions.  Secondary hyperhidrosis: There are a few people who have increased sweating due to physical disorders, which are called secondary hyperhidrosis, such as hyperthyroidism, endocrine disorders, psychiatric disorders, and endocrine imbalance during menopause.