Pressure and postural hyperhidrosis is the sweating response to pressure on one side of the body during position changes and lateral recumbency. It is a manifestation of hyperhidrosis. Hyperhidrosis is a disorder in which excessive sweat gland secretion is caused by sympathetic hyperexcitation. The sympathetic nerve governs sweating throughout the body. Under normal circumstances, the sympathetic nerve regulates body temperature by controlling sweating and heat dissipation. In hyperhidrosis, however, sweating and facial flushing are completely out of control. Hyperhidrosis and facial flushing leave the patient in a daily state of helplessness, agitation or panic. What are the causes of stress and postural hyperhidrosis? Generalized hyperhidrosis can be an abnormal physiological response or one of the symptoms of certain diseases such as hyperthyroidism and diabetes. Localized hyperhidrosis can be due to sympathetic nerve damage or an abnormal response with increased secretion of choline acetate, resulting in excessive sweat secretion from small sweat glands. (A) Pathogenesis Hyperhidrosis can be broadly classified into three categories in terms of pathogenesis. One is due to systemic diseases such as endocrine disorders (hyperthyroidism, diabetes mellitus, hyperpituitarism, etc.), neurological diseases, some infectious diseases (malaria, tuberculosis, etc.) and weakness due to long-term illness. As soon as these systemic diseases are controlled the excessive sweating can be resolved. The second is psychogenic sweating, caused by high tension and emotional excitement, is due to sympathetic dysregulation, and the internal use of some sedative drugs (such as atropine, probenecid, belladonna combination, etc.) has a temporary effect, but has side effects such as dry mouth. The third is gustatory sweating, which is another physiological phenomenon, such as excessive sweating caused by eating certain stimulating foods (chili, garlic, ginger, cocoa, coffee), which generally does not need to be treated and only requires abstinence from eating. (B) Pathogenesis Hyperhidrosis mainly refers to excessive sweating from multiple parts of the small sweat glands, often involving the axillae, palmoplantar and groin, the causes can be divided into neurogenic and non-neurogenic, neurogenic refers to the control of nerve reflexes; in addition to local thermal stimulation, non-neurogenic refers to the role of peripheral non-neurogenic factors – glandular level excitation reaction.