Newborn babies spitting up yellow-brown secretion may be related to newborns spitting up amniotic fluid, neonatal hypopharyngeal syndrome, congenital megacolon, etc. According to the cause of the disease, you can choose temporary observation, general treatment as well as medication. 1. Spitting up amniotic fluid: it is a normal manifestation, usually no special treatment is needed, about 1~2 days, the symptoms will gradually disappear and return to normal. When spitting up amniotic fluid, you can drink more water to accelerate excretion. 2. Neonatal hypopharyngeal syndrome: Amniotic fluid swallowed into the stomach may be contaminated by fetal feces and bacteria, which may irritate the gastrointestinal mucosa and easily cause neonatal hypopharyngeal syndrome, which leads to vomiting, and the secretion will be yellowish-brown or coffee-colored. No special treatment can be done for the time being. If the symptoms are serious, treatment such as gastric lavage should be given. 3. Congenital megacolon: constipation is the most important symptom of congenital megacolon, in addition, the disease can also lead to vomiting in newborns, which usually requires surgery for treatment. Newborn babies vomit yellow-brown discharge may also be acute digestive system inflammation and other causes. Newborn babies with vomiting symptoms, need to consult the doctor in a timely manner, after a clear diagnosis for targeted treatment, to avoid delayed treatment.