The spread of cancer cells to the lymphatic system usually indicates that the condition is more serious and requires timely and targeted treatment. Lymphatic spread of cancer cells means that the cancer cells have metastasized, which suggests that the disease has become more serious. It is necessary to determine whether the metastasis is distant or localized. If the metastasis is widespread, such as when the cancer cells invade important organs such as liver, lungs, bones, etc., the patient’s life can only be prolonged as far as possible by means of radiotherapy and chemotherapy. In case of peripheral lymph node metastasis, there is a possibility of surgical treatment. Preoperative adjuvant chemotherapy can be done first to shrink the metastatic lymph nodes and reduce the risk before deciding whether surgical treatment can be carried out. If the patient has cancer cells spreading to lymph, he/she should consult the doctor in time and actively cooperate with the treatment under the doctor’s guidance, taking into account the specific situation. At the same time, keeping a good mindset, paying attention to rest and supplementing nutrition according to doctor’s instructions are all beneficial to the body.