Stage 4 kidney cancer belongs to advanced stage, advanced kidney cancer can not be cured completely, and its treatment aims at improving patients’ life quality and prolonging their life span, and often requires comprehensive treatment. For patients with advanced kidney cancer, even if metastasis has occurred, they can consider whether surgery can be performed depending on the specific situation, and tumor reduction surgery can be achieved by removing the kidney through surgery. At the same time, after removing the kidney with tumor, genetic test can be performed, and according to the result of genetic test, drugs can be used for targeted therapy. At present, drug treatment for advanced kidney cancer also includes cytokine therapy, immunotherapy, chemotherapy, radiotherapy and other methods. When patients have kidney cancer, it is recommended to go to regular hospitals for examination as soon as possible, so as to detect and treat it as early as possible.