At night always feel the symptoms of chest tightness, to consider the following possibilities: 1, the possibility of the existence of coronary heart disease, myocardial ischemia, there is the possibility of prone angina pectoris. At this time, we must do electrocardiogram or 24-hour electrocardiogram monitoring to observe whether the electrocardiogram has dynamic changes, if necessary, can be performed coronary angiography or CTA to clarify the diagnosis; 2, at night, if the symptom of chest tightness in bed, this time to consider whether there is the possibility of lying down limitations, patients with heart failure often lead to the emergence of some of the symptoms of lying down limitations, chest tightness The possibility of shortness of breath. At this time we do chest X-ray, cardiac ultrasound, will suggest that there is a possibility of heart enlargement, need to give patients to reduce the heart load and other treatments; 3, the emergence of symptoms of chest tightness at night should also be considered whether there is a functional possibility, because at night when the night is late, the patient’s mood will have some fluctuations, which may lead to some emotional, stress and other aspects of the problem, and the emergence of chest tightness, the diagnosis of this disease depends on the exclusion of the diagnosis of this disease. The diagnosis depends on the exclusive diagnosis.