Low mean red blood cell volume is commonly seen in microcytic hypochromic anemia, which is mainly treated with dietary supplements and drugs to correct anemia. A single abnormal test result cannot be used as the basis for diagnosis, but should be combined with the patient’s condition and other auxiliary tests to make a comprehensive judgment. 1. The average red blood cell volume refers to the average volume of each red blood cell, referred to as MCV, with a normal range of 80~100fl; when MCV＜80fl, it often suggests microcytic hypochromic anemia, and microcytic hypochromic anemia is divided into iron-deficiency anemia, anemia with impaired production of bead protein, and so on. 2. When suffering from iron-deficiency anemia, adequate nutrition should be supplemented, and more high-protein foods should be eaten, such as lean meat, fish, eggs and milk, etc.; in severe cases, oral iron can be taken under the guidance of physicians, such as ferrous sulfate, ferrous gluconate, etc., and iron can be injected into the muscle, such as iron dextran, etc., if necessary. 3. In the case of dysgenerative anemia, red blood cell transfusion or hematopoietic stem cell transplantation can be used. When the average red blood cell volume is found to be low, it should seek medical treatment in time, and standardized treatment should be carried out after clear diagnosis by professional doctors, do not take medicine by yourself to avoid adverse reactions.