Topical hydroquinone cream is a skin discoloring agent and can be used to get rid of blemishes. Hydroquinone cream belongs to the skin discoloring agent, can play a role in removing spots, but mainly used for chloasma, freckles and post-inflammatory hyperpigmentation spots and other pigmented spots. The principle of hydroquinone cream is to reduce the activity of tyrosinase as well as to interfere with and prevent the formation of melanin, so as to play a role in the treatment of pigmented skin diseases, and at present, it is mainly formulated to be used at a concentration of 2%-4% in clinical practice. However, some patients in the use of hydroquinone cream, prone to burning sensation, local allergic reactions and other adverse phenomena, once these adverse reactions, need to stop immediately, and give treatment; in addition to the existence of allergies to the drug, or children under 12 years of age and pregnant women are prohibited from using. During the use of the drug, it is necessary to pay attention to the area of each use should not be too large, can not be used for the eyes and wounds around the lesions; in the use of the drug, to avoid sunlight, so as not to cause the appearance of freckles. For patients who need to use hydroquinone cream to treat diseases, need to be under the guidance of a professional doctor, follow the doctor’s instructions for use.