When the endometrium is thick after menopause, it is not possible to take 7 days of progesterone first, and diagnostic scraping can be performed first under the guidance of the doctor. After menopause, ovarian function declines, estrogen and progesterone levels will also decline rapidly, and the uterine lining will no longer have cyclical changes. Therefore, when the ultrasound examination indicates that the endometrium is thick, diagnostic scraping and histopathological examination of the endometrium should be carried out according to the doctor’s instruction to exclude endometrial cancer, and only after the exclusion of endometrial cancer can medication be given under the guidance of the doctor. Menopausal women should develop a good routine and establish a healthy lifestyle, such as insisting on physical exercise, healthy diet, increasing the time of sun exposure, and increasing the intake of proteins and calcium-rich foods to prevent osteoporosis. When irregular vaginal bleeding and other abnormalities occur after menopause, you need to go to the hospital in time and follow the doctor’s instructions to deal with the treatment.