Fever after MMR vaccination can be treated with physical cooling and medication. Generally 1 ~ 2 weeks after vaccination, there can be a transient fever reaction. Mild febrile reaction, usually lasts 1 ~ 2 days can be relieved on their own, do not need to deal with, if necessary, appropriate rest, drink plenty of boiled water, pay attention to warmth, to prevent secondary infections; for moderate febrile reaction or fever for more than 48 hours, can be used to physical methods or medication symptomatic treatment. For children with fever but body temperature <38.5℃, physical methods such as applying warm water to the forehead of the child and reducing the amount of clothing worn can be used to lower the temperature, and children should be encouraged to drink more water, and the body temperature of some children can be gradually decreased; for babies with temperature ≥38.5℃, antipyretic medicines such as ibuprofen and acetaminophen should be used for antipyretic treatment under the guidance of doctors. After the MMR vaccination, the body immunity is relatively weak, need to pay attention to whether there are secondary infections, for secondary viral infections, generally no special medication, give symptomatic treatment can be; when secondary bacterial infections, can follow the doctor's instructions to use cefixime, cefuroxime and other drugs anti-infection treatment. It is recommended that once the parents found that the baby after the MMR vaccine fever, take the baby to the doctor in time to improve the relevant examination, standardized treatment. The use of drugs should be used under the guidance of a doctor, do not blindly use drugs.