Foot swelling caused by Hashimoto’s thyroiditis may be anterior tibial mucous edema, which may recover with treatment, but if the foot swelling is not anterior tibial mucous edema but is due to other causes such as hypoproteinemia, then treating Hashimoto’s thyroiditis will not alleviate the symptoms of foot swelling. Hashimoto’s thyroiditis is a chronic autoimmune thyroid disease, which can lead to enlarged thyroid glands and hypothyroidism, which in turn can lead to symptoms of anterior tibial mucous edema in the feet. Therapeutically, levothyroxine tablets can be used in patients with hypothyroidism to relieve the symptoms of hypothyroidism and anterior tibial mucous edema. If Hashimoto’s thyroiditis is accompanied by other diseases such as hypoproteinemia or varicose veins in the lower limbs, it may also lead to swelling of the feet, in which case treatment of Hashimoto’s thyroiditis is usually not able to relieve the swelling of the feet, and the swelling of the feet can be relieved only through the infusion of albumin to treat hypoproteinemia, and elevation of the lower limbs to treat varicose veins in the lower limbs, or through surgical treatments. If a patient with Hashimoto’s thyroiditis develops swelling of the feet, it is important to consult a doctor and follow his or her instructions.