Case: Mr. Hou, 54 years old, a teacher, 4 years ago, he began to walk slower, back pain, leg pain, neck pain, traveled a lot of places to see a lot of doctors, checking the cervical spine lumbar vertebrae and knee joints, nothing serious, and then, transferred to a hospital to prepare for lumbar surgery, encountered a specialist to look at the course of the disease suggested that he go to the Department of Neurology to see, to rule out Parkinson’s disease and then consider surgery. After diagnosis, he took medication for 15 days and looked like a normal person, and resumed work 3 months later. Parkinson’s disease is a movement disorder with typical symptoms: bradykinesia, resting tremor and myotonia. Bradykinesia manifests itself in activities that are difficult and slow at first, such as walking and not being able to take a step, etc.; resting tremor often starts in one side of the hand and spreads to the whole upper limbs, lower limbs, and face, and is mostly asymmetrical. Many patients have “counting bills” or “rubbing pills” kind of tremor in the fingers when they are still, and the symptoms disappear when the fingers are moving freely; myotonia refers to the stiffness of the patient’s muscles, and if it occurs in the face, it will be manifested as a stiff expression, less blinking, commonly known as “mask face”, and it is also known as “mask face”. “Mask face”, limbs also feel very heavy or no strength when moving. Decreased sense of smell is also a typical manifestation of early Parkinson’s disease Decreased sense of smell can appear 3~7 years earlier than the motor symptoms of Parkinson’s disease, and about 90% of patients with Parkinson’s disease have decreased sense of smell. The latest Clinical Diagnostic Criteria for Parkinson’s Disease lists hyposmia as one of the supporting criteria for the diagnosis of Parkinson’s disease. If an older person finds that he or she has a reduced sense of smell and has bradykinesia, resting tremor, or myasthenia gravis, he or she should go to the Parkinson’s Specialty Clinic at the local hospital as soon as possible to get a clear diagnosis of Parkinson’s disease at an early stage of the disease. Constipation, depression, sleep, hand and foot movement may also be related to Parkinson’s disease Parkinson’s early typical symptoms in addition to the sense of smell loss, walking feet, hand tremor, constipation, depression, sleep behavioral abnormalities and Parkinson’s disease correlation is also strong. Data show that the risk of Parkinson’s disease in constipated people is three times higher than in non-constipated people, and some Parkinson’s disease patients experience constipation 10 to 20 years before the onset of typical motor symptoms, while depression can appear more than twenty years before motor symptoms. Data show that up to more than half of the Parkinson’s disease patients with sleep behavioral abnormalities, for example, sleep punching and kicking, some patients will be practicing in their sleep, “shadowless foot”, will be the old partner kicked out of bed, the patient will also have nightmares, dreaming, and so on. Therefore, for the long years by constipation, depression, sleep, hand and foot movement and other situations troubled by the elderly, should pay close attention to their own whether there is a slow movement, hand tremor and other situations, once found to be as early as possible to seek medical attention. Parkinson’s Disease: Early medication can help Parkinson’s Disease progresses and worsens over time, severely affecting a person’s ability to move, think, and feel emotionally. Parkinson’s disease in the early stage of the disease progresses quickly, to the late stage of the development of slow, so if you can be in the early scientific treatment, not only can improve the symptoms, but also may achieve the effect of delaying the progress of the disease, to improve the quality of life is particularly important. It is found that Parkinson’s disease patients who start treatment within 1~3 years after the onset of the disease have significantly better self-care ability, mobility and quality of life than those who start treatment 4~6 years after the onset of the disease. In the early stage, patients can choose medication such as Medopa and Senflo; after the on-off phenomenon and anisocoria appear when the effect of medication diminishes, they can choose deep brain electrical stimulation surgery (pacemaker surgery, DBS) treatment, which can effectively improve the quality of life of patients with Parkinson’s disease.