According to the international BCLC staging (Barcelona staging), liver cancer with portal vein thrombosis is classified as stage C (the tumor has invaded blood vessels or metastasized), which is also known as advanced liver cancer. The growth of portal vein thrombus means that the tumor has reached an advanced stage, the condition is more complicated and the treatment effect is worse. Overseas countries often do not operate on patients with liver cancer with portal vein thrombus. However, for Asian patients, if they do not undergo surgery, the treatment effect is not very good if they only take some targeted drugs. Moreover, targeted drugs are very expensive and the cost is so high that the burden on the family is usually very heavy. Domestic doctors (when the patient’s condition permits) usually adopt surgery to improve the patient’s symptoms, quality of life and long-term treatment results.