We all love beauty. In the past two decades, the progress of science and technology has made it possible for human beings to “grow back”. Especially in recent years, with the continuous development of minimally invasive technology, such as rhinoplasty in the past need to open surgery to realize the cosmetic operation, now only need to be injected with a “cosmetic injection”, you can achieve similar results. Nowadays, this “cosmetic injection” is more and more popular among beauty lovers, however, unbeknownst to them, behind the beauty of the same time also lurks the risk. Hyaluronic acid is China’s approval of the injection preparation can be used for facial micropigmentation, in the regular medical institutions by the regular plastic surgeon to carry out injections, in most cases for the beauty seekers to bring about facial improvement. However, it has been reported that some unscrupulous beauty institutions have used “Oxymethadine” as hyaluronic acid, which is an injectable cosmetic product expressly prohibited for use, and once used, the risk is incalculable. On the other hand, not only fake hyaluronic acid, but also other micropigmentation injections, if the operation is not standardized, there are still many unknown risks, permanent blindness is one of them. Early cases of blindness caused by cosmetic injections have been reported in foreign medical literature. Blindness is the most serious complication of facial injections of cosmetic fillers. Due to the extensive traffic of blood vessels in facial organs, if fillers are inadvertently injected directly into the facial arterial vasculature, or if the injection speed is too fast, or if the injection pressure is too high, resulting in the infiltration of fillers into the blood circulation, the viscous fillers may form embolisms in the bloodstream, reverse the flow of blood along the arteries, and, in individual cases, enter into the ophthalmic arterial branches, block the central retinal artery, and cause Central retinal artery obstruction can lead to blindness within minutes; if the embolus widely obstructs the ciliary artery of the eye, it may also cause ischemia of the entire eye, and ultimately atrophy of the eye; if the embolus obstructs the other terminal arteries of the face, it can cause ischemia, ulceration, and necrosis of the skin in the corresponding area. Once the central retinal artery obstruction occurs, the patient can lose the sense of light within a few minutes, ophthalmologists can check the fundus of the eye to see the whole retina ischemia, pallor, edema, because the retina is metabolically active nerve tissue, ischemia for a long time will be irreversible loss of function, and the regeneration of the nerve tissue is very difficult, so patients with central retinal artery obstruction to the doctor’s eyesight is often irretrievable. Overseas medical literature has so far reported 34 cases of facial injections leading to blindness, of which 15 cases were autologous fat transplantation, another 4 cases of hormone injections, 3 cases of collagen injections, 3 cases of silicone injections, 2 cases of poly L-lactic acid injections, 2 cases of hyaluronic acid injections, 2 cases of polymethylmethacrylate injections, 1 case of hydroxyapatite injections, 1 case of paraffin injections, as well as 1 case of injections of unknown substances. Among the 19 cases of blindness caused by micropigmentation injections, in addition to 7 cases of rhinoplasty injections, there were 4 cases of injections between the eyebrows, 3 cases of scalp injections, 2 cases of forehead injections, 2 cases of hairline injections, and 1 case of injections around the eyes; it can be seen that rhinoplasty injections have the highest risk, and injections in other parts of the body are not absolutely safe either. The above data is only based on statistics reported in the literature, however, only a small portion of the large number of micropigmentation injections carried out every day around the world are registered. Especially in our country, where the underground cosmetic market is very active, we hypothesize that the actual incidence of blindness due to cosmetic injections is higher than reported in the literature. In addition to this, we have seen a patient in outpatient clinic who had a sudden and significant loss of vision in both eyes after breast augmentation, and after ophthalmologic examination, we found multiple small retinal blood vessel embolisms in the macular region of both eyes and macular ischemia. But even more frightening is that this patient later also had a pulmonary embolism, seriously life-threatening. Who would have thought that a small breast augmentation surgery could lead to such serious consequences? As the guardians of light – ophthalmologists, we would like to remind the majority of beauty lovers: beauty has risks, plastic surgery need to be careful; beauty is valuable, the price of light is higher!