Adrenal tumors have a complex and varied symptomatology, which is related to their structure and function. The adrenal cortex secretes aldosterone, glucocorticoids and sex hormones, and the medulla secretes epinephrine, norepinephrine and dopamine. Tumors occurring at different sites cause different diseases and symptomatic manifestations. Primary aldosteronism, cortisolism and catecholamines are the most common. Typical symptoms of adrenal tumors are: 1. Primary aldosteronism: a disease caused by adrenocortical bulbous band tumor. It manifests as hypertension, muscle weakness, persistent hypokalemia in 70% of patients and intermittent in 30%. Heartburn, thirst, polydipsia and polyuria, with increased nocturia as the main cause. 2.Cortisolism: Symptoms caused by adrenocortical reticular band tumor. There are mostly centripetal obesity, full-moon face, buffalo back (increased fat at the back of neck and both shoulders), thin skin, hairy, purple lines in armpits, sides of lower abdomen and thighs, and the patients mostly have high blood pressure, fatigue, and lumbar and leg pain. Female patients show typical symptoms such as amenorrhea or menstrual disorders and osteoporosis. 3.Catecholamine disease: symptoms caused by increased catecholamine due to pheochromocytoma. It mainly manifests as elevated blood pressure and changes in basal metabolism. High blood pressure is characterized by persistent elevation of blood pressure with paroxysmal extreme elevation. There are often symptoms such as dizziness, headache, chest tightness, chest pain, panic, blurred vision, nervousness and anxiety. 4.Gonadal anomalies: caused by cortical tumors, divided into genital enlargement precocious puberty, female pseudohermaphroditism, female masculinization. 5.Other malignant tumors are mostly accompanied by wasting: weakness, decreased appetite, night sweating and other symptoms. Regardless of the clinical symptoms of adrenal tumors, the diagnosis mainly relies on imaging and endocrine examination, and the confirmation of the diagnosis needs to rely on pathological examination, and after the diagnosis is clear, it is necessary to actively treat it in order to have a good effect.