The generic name of Dermatopin is Dexamethasone Acetate Cream Compound. Itching of the scrotum and penis and the appearance of granulation on the foreskin after the application of this product are mainly considered to be related to allergic reaction, glans penis, folliculitis, and so on. 1. Allergic reaction: after applying compound dexamethasone acetate cream, some patients may have some adverse reactions, such as rash, tingling, etc., and even small granules may appear. 2. Foreskin glansitis: under the repeated stimulation of inflammation, it can lead to abnormal proliferation of local skin and the emergence of granulomatous polyps. 3. Folliculitis: mainly caused by the blockage of follicular ducts, it can also lead to redness, swelling and granulation-like bumps in the affected area, accompanied by itching, tingling, fever and other symptoms. The appearance of granulation on the foreskin may also be related to other factors. It is recommended that patients seek medical attention to confirm the diagnosis and follow the doctor’s instructions for treatment.