1, gallbladder stones induced acute cholecystitis, acute pancreatitis or other serious complications 2, atrophic cholecystitis Hou Dongsheng, Minimally Invasive General Surgery Department, The First Hospital of Guangzhou Medical University 3, porcelain gallbladder 4, diabetes combined with gallbladder stones (when diabetes has been controlled) 5, adenomyoma and adenoma of gallbladder, or combined with stones 6, gallbladder stones embedded in the neck of the gallbladder resulting in bile duct incompetence. 7.Non-stone cholecystitis with gallbladder dysfunction 8.Gallbladder polyps >1CM in diameter, or increase significantly within a short period of time, or combined with symptoms of cholecystitis, or pathology suggesting active hyperplasia or severe hyperplasia 9.The elderly or those with cardiopulmonary dysfunction combined with stones, still able to tolerate surgery.