Indiscriminate consumption of Gui Fu Di Huang Wan may aggravate the condition in the absence of the right remedy, producing adverse reactions such as fever, diarrhea, vomiting, and itching of the skin; therefore, it is recommended to take the medication under the guidance of a physician. Gui Fu Di Huang Wan is made up of cinnamon, epimedium, yam and cornelian cherry, which has the effect of warming and tonifying the kidney yang (warming and replenishing the yang energy of the kidneys), and has a therapeutic effect on the symptoms of lumbar and knee coldness and pain caused by kidney yang deficiency, frequent urination, and tiredness of the limbs. However, if the patient identification does not belong to the kidney yang deficiency, but the kidney yin deficiency or real heat syndrome patients taking this drug, will aggravate the condition, produce fever, diarrhea, vomiting and other symptoms, for the cold during the taking of this drug will aggravate the symptoms of fever; in addition, for allergic patients, may produce itchy side effects; for pregnant women and children need to be guided by a physician to use the drug. Gui Fu Di Huang Wan in the case of non-symptomatic random drug, may produce the above consequences, so it is recommended to feel unwell in time to consult a doctor, in the doctor under the guidance of the identification of medication, do not take drugs to delay the condition.