For patients with underlying liver disease, if the patient has a cold, it is recommended that the patient consider a cold preparation of Chinese medicine for active treatment and take as little western medicine as possible to treat the cold. For liver protection tablets, it is recommended that they be taken separately from cold medications, at least two hours apart. For patients with underlying liver disease, it is recommended that patients try not to take Western medicine, and it is recommended that when you have a cold, you take more Chinese medicine such as 999 cold and flu, or Jing Fang granules, Xiao Chai Hu granules and other drugs for treatment. Do not take drugs for too long, it is recommended that after a week, if the patient’s symptoms worsen, we should consider consulting in the hospital, if necessary, infusion of antibiotics and anti-inflammatory drugs for active treatment. If necessary, the patient should have blood tests for routine blood and liver function to see if the patient has elevated white blood cells, elevated neutrophils, and elevated lymphocytes in combination. In addition, for liver function, if the patient has elevated glutathione and glutamic oxalacetic transaminase, the patient should be treated with liver-protective drugs such as reduced glutathione and diammonium glycyrrhizate, if necessary.