Severe constipation can lead to many hazards, as follows: 1, can cause anorectal disorders, constipation when defecation difficulties fecal dryness, can directly cause or strengthen anorectal disorders such as proctitis, anal fissure, hemorrhoids, etc.; 2, gastrointestinal nerve disorders, constipation, fecal retention of harmful substances absorption, can cause gastrointestinal nerve disorders, and lead to loss of appetite, abdominal pain, fullness, belching, mouth bitter, anal exhaust 3, can induce cardiovascular, cerebrovascular disease attacks, clinically about constipation due to force to increase abdominal pressure, holding the breath caused by the difficulty of defecation and caused by cardiovascular and cerebrovascular disease attackers increased year by year, can induce angina pectoris, myocardial infarction attacks, as well as cerebral hemorrhage, stroke, sudden death, etc.; 4, prone to colon cancer, probably because of constipation and intestinal carcinogenic substances can not be eliminated for a long time, according to data show that About 10% of patients with severe constipation suffer from colon cancer; 5, can lead to neurasthenia, constipation patients can have irritability, restlessness, insomnia and other symptoms; 6, cause dysmenorrhea, chronic constipation patients due to long-term pelvic muscle stimulation, often can cause dysmenorrhea; 7, loss of libido, long-term constipation patients can have loss of libido leading to impotence and premature ejaculation in men, women’s sexual frigidity, prompting a decline in the quality of sexual life; 8, affect the beauty of patients with constipation due to fecal matter can not be eliminated. Constipation patients due to long-term retention of fecal blocks in the intestinal tract, abnormal fermentation, corruption can produce a large number of harmful toxins, acne, facial pigmentation, rashes, etc.; 9, can produce body odor, the accumulation of toxins can cause halitosis or body odor; 10, causing sudden death, especially hypertension, coronary heart disease and other cardiovascular and cerebrovascular disease patients, severe constipation, anal rage after earning a sharp rise in blood pressure, resulting in stroke or even sudden death.