Patients with cancer may have hyperpigmented, dark-colored skin. If some are accompanied by obstructive jaundice, the skin will be yellow. In addition, cancer patients may have anemia because of heavy consumption, and this time will show an anemic appearance and have pale skin. Of course, there are also some early stage cancer patients who do not have obvious skin changes. Cancer is a systemic disease that may bring about abnormalities in various systems of the body, and it needs to be taken seriously when it is manifested in the skin. If there is anemia, it needs to be treated with blood supplementation drugs, and in severe anemia, blood transfusion is needed. In addition, if there is an allergic skin reaction, it is necessary to consider the adjustment of drugs for cancer treatment, or the application of anti-allergic drugs can improve the symptoms. If the skin of a cancer patient shows jaundice symptoms are more severe, further examination is needed, and treatment such as liver protection, yellowing reduction and interventions can be considered to reduce jaundice.