Congenital hypertrophic pyloric stenosis is a common condition in newborns. Its symptoms appear around 2 weeks after birth. Vomiting is the main symptom, initially only as retching, followed by jet vomiting. It starts with occasional vomiting, and as the obstruction worsens, vomiting occurs after almost every feeding, and the vomit is mucus or milk. Due to malnutrition and dehydration, the infant is visibly thin, with loose wrinkled skin, reduced subcutaneous fat and a distressed look of depression. Ultrasound examination can reveal hypertrophy of the muscular layer, and upper gastrointestinal tract imaging can clarify the diagnosis. Congenital hypertrophic pyloric stenosis, in clinical practice, is a common disease in newborns. Parents need to have a better understanding of these diseases. Minimally invasive laparoscopic treatment of congenital hypertrophic pyloric stenosis method: After the preoperative diagnosis is clear, supportive therapy is actively used to correct water and electrolyte disorders and malnutrition, and a gastric tube is left in the morning of surgery for gastrointestinal decompression. A closed endotracheal anesthesia was used. First, a 0.5 cm incision was made at the upper edge of the umbilical fold, and a pneumoperitoneal needle was inserted, and about 1.5-2.0 liters of carbon dioxide was injected to create an artificial pneumoperitoneum with a pneumoperitoneal pressure of 1.2-1.5 kPa, and then the pneumoperitoneal needle was withdrawn, a 0.5 cm diameter Trocar was placed in the umbilicus, and a laparoscope was placed. Under laparoscopic surveillance, a subcutaneous 0.3 cm skin incision was made under the right costal margin and the subxiphoid process, and a 0.3 mm diameter Trocar was inserted and a 0.3 mm diameter operating forceps was placed. The special separator forceps were inserted into the myotomy incision. The entire pyloric muscle is separated bluntly one by one until the mucosa is completely expanded. If intraoperative bleeding can be stopped by electrocoagulation, mucosal bleeding can be stopped by compression. After checking that there is no damage to the mucosa, the Trocar is removed one by one, carbon dioxide is released, the pneumoperitoneum is eliminated, the incision is disinfected, and the incision is glued with medical adhesive, and the operation is completed. Postoperative feeding should be started in the following morning, with sugar water first, from little to much, and milk gradually for 24 hours, and to a full amount for 2-3 days. Most of the postoperative vomiting is the result of rapid increase in diet, which should be reduced and then gradually increased. The minimally invasive laparoscopic treatment of congenital hypertrophic pyloric stenosis carried out by the Department of Pediatric Surgery is less traumatic for the child, with quick recovery and fewer complications, and leaves no scars after surgery, completely eliminating the inferiority complex and employment worries caused by scars in the child’s adulthood.