Anti-inflammatory drugs such as metronidazole can be taken by a 58-year-old woman with a painful and itchy vaginal opening. If there is an infection of the vulva, 58-year-old women will show the infection of the vaginal opening pain and itching, and there may be abnormal secretions, etc. At this time, you can be treated by oral metronidazole and other antibiotics. In addition, 58-year-old women in the postmenopausal period, usually the body’s estrogen level is low, can not give the local mucous membrane normal nutrition, may cause vaginal atrophy, pain and itching and other discomforts, at this time do not need to eat anti-inflammatory drugs, need to be applied locally estrogen ointment for treatment. If the 58-year-old woman appeared vaginal opening pain and itching situation continues to not be able to relieve, it is recommended to go to the hospital in time to see a doctor, under the guidance of the doctor for standardized treatment. The above drugs should be used under the guidance of a doctor, and unauthorized use of drugs is prohibited.