Blood sedimentation generally refers to the erythrocyte sedimentation rate, and the index in 40~50mm/60min may be abnormal. Usually, the normal reference range of erythrocyte sedimentation rate is less than 15mm/60min for men and less than 20mm/60min for women, while both men and women with erythrocyte sedimentation rate of 40~50mm/60min are above the normal range. Usually, the accelerated erythrocyte sedimentation rate can be divided into physiological and pathological, physiological acceleration is mostly seen in infants and young children, female menstruation, pregnancy 3 months to postpartum and so on. Pathological acceleration is mostly caused by active rheumatic disease, acute inflammation, anemia, severe tissue destruction, malignant tumors and other conditions. At the same time, the speed of erythrocyte sedimentation rate can also assist in monitoring the changes in the condition, generally in the active period of erythrocyte sedimentation rate will accelerate, after the condition improves will slow down. It is recommended that patients with erythrocyte sedimentation rate of 40~50mm/60min, after exclusion of physiological phenomena, to clarify the cause of the disease in a timely manner, to take targeted treatment.