Ankle pain can be treated with braking, rest, oral medications, and surgery if it is caused by trauma. If it is caused by ankle arthritis, it can be treated with medication as well as surgery. Trauma can cause damage to the ligaments around the ankle joint, which can lead to significant pain, swelling of the tissues, and bruising under the skin. It is necessary to pay attention to rest, it is best to do bed rest, the pain is obvious can be oral anti-inflammatory analgesic drugs to ease the pain, such as nimesulide, diclofenac sodium and so on, can also be taken orally to promote the swelling of the heptadecyl saponin sodium subside. If the injury is serious enough to cause complete rupture of the ligament or even ankle fracture, it can be treated by surgery, such as ligament repair and internal fixation of the fracture by incision and reduction. If the pain is caused by ankle joint arthritis such as osteoarthritis, rheumatoid rheumatoid arthritis, gouty arthritis, we should pay attention to proper rest, oral anti-inflammatory and analgesic drugs to relieve pain. At the same time to actively treat the primary disease, such as rheumatoid rheumatoid arthritis oral anti-rheumatic drugs such as leflunomide, paeonia lactiflora total glycosides and so on. In case of gouty arthritis, oral drugs such as febuxostat and colchicine can be taken. Serious joint damage can also be treated with surgery, such as artificial ankle replacement or joint fusion. If the physiological pain in the ankle joint is caused by excessive activity, it can usually be fully recovered after appropriate rest and hot compress treatment. If ankle pain occurs, it is recommended that the patient go to the hospital for medical examination to clarify the cause of the disease and receive regular treatment.