Severe tricuspid regurgitation is caused by severe tricuspid valve insufficiency, and a large amount of blood regurgitates from the right ventricle to the right atrium during heart contraction will cause severe right heart failure. The main clinical manifestations are loss of appetite, weakness, swelling of both lower limbs, and even pleural effusion and abdominal effusion. Most of the causes of tricuspid valve insufficiency are due to rheumatic heart disease, degenerative changes in the tricuspid valve, followed by some immune system diseases that cause valve insufficiency, and infective endocarditis, which can also cause tricuspid valve insufficiency. If severe tricuspid regurgitation is found, the cause should be actively sought and treated, and if the symptoms of severe tricuspid regurgitation persist after the cause is eliminated, surgical valve replacement or valvuloplasty should be performed.