Eyelid swelling, leg swelling clinically common causes may have the following conditions: First, hypothyroidism patients, can be due to the body’s energy metabolism is slow, and cause eyelids, legs within the loose tissue accompanied by the formation of edema. Patients can improve the thyroid function examination to clarify the nature of lesions, and then supplement levothyroxine tablets appropriately to maintain the body’s thyroxine at the normal level, which can effectively reduce the swelling symptoms of eyelids and legs. Secondly, patients with middle and late stage of tumor can be in the state of low protein malnutrition for a long time because of low energy intake, which is manifested by the water in the blood vessels seeping into the tissue interstices, and the swelling of eyelids and legs will appear. At this time, the patient’s condition is late, even if the supplementation of large amounts of albumin, strengthen the intravenous nutritional support, the prognosis is often poor, the overall survival time is usually about 3-6 months. There are other nephrogenic and hepatic edema, and internal medicine consultation is recommended to clarify the etiology and treatment.