The clinical manifestations of splenomegaly vary depending on the primary cause. If the enlarged spleen is caused by portal hypertension, it is often accompanied by liver disease, so various clinical manifestations of the liver may occur, such as cirrhosis, hepatitis B virus infection, jaundice, and even a series of gastrointestinal changes such as abdominal distention and diarrhea, etc. If the enlarged spleen is caused by a blood disorder, it may produce fever and even changes in the blood picture or platelets, for example. Frequent bleeding from various parts of the body, nosebleeds, wounds that do not heal easily after breaking, etc. If the enlargement of the spleen is due to infection. It is often accompanied by fever and even systemic toxicity and changes in blood picture. In the case of neoplastic diseases, there are often various clinical manifestations of tumors. If the spleen is enlarged, it is important to treat the original disease in a timely manner. You should also pay attention to improving your diet by eating more fruits and vegetables and not eating spicy and stimulating foods. If the enlargement of the spleen is not relieved, surgical removal can be considered for complete cure. In conclusion, the clinical manifestations of splenomegaly are different in each case. Careful identification must be made based on the patient’s primary disease.