Premature closure of the cranial suture, also known as cranial stenosis or narrow craniosynostosis, is a collective term for a group of disorders in which the premature closure of the cranial suture in different areas affects the normal development of the skull and brain. The incidence in newborns is 0.25/‰, and male patients predominate, accounting for 61% to 80% of the total number of patients, especially in sagittal or frontal suture premature closure. The outer layer of the dura mater is the origin of the cranial bones, the bones of the skull cap are membrane internalized bones, and the bones of the skull base are cartilaginous internalized bones. Normal fontanelle closes after birth, posterior fontanelle closes at 3 months, anterior fontanelle closes at about 2 years of age; bone sutures develop at about 1 year of age, and at 2 years of age there is a fiber connection between the bone sutures, the frontal suture and part of the sagittal suture close naturally in the second year after birth, the sagittal suture closes completely and the coronal suture and herringbone suture close at about 40 years of age, the squamous suture and occipital mammary suture and pterotemporal suture only partially close at 70 years of age. In addition to the premature closure of the sutures in the fornix of the skull, the sutures in the skull base, maxillofacial and orbital sutures can also be involved in premature closure, resulting in craniofacial deformity. Premature closure of the cranial suture causes restricted development of the cranial contents and affects the growth and development of the brain, which is the main cause of craniofacial deformity and neurological symptoms and signs. The cause of primary craniosynostosis is unknown. It may be a genetic defect of cranial growth in utero, often combined with cleft lip, cleft palate, syndactyly or syndactyly and other deformities. 2, metabolic craniosynostosis such as rickets, hyperthyroidism, hematologic erythrocytosis or thalassemia, idiopathic hypocalcemia, mucopolysaccharide storage disease, mucolipidosis, etc. 3.Medical factors Premature closure of cranial suture in children with hydrocephalus secondary to drainage by low pressure shunt.