With the progress and development of science and technology, especially the exploration of various maladies after cholecystectomy, it is suggested that the gallbladder has extremely complex and important functions and is an indispensable and alternative important digestive and immune organ. To the best of our knowledge, the gallbladder has at least the functions of storage, concentration and contraction. It also has, of course, complex chemical and immunological functions. The gallbladder concentrates dilute hepatic bile 30-fold, stores it in the gallbladder, and drains it into the intestine to participate in digestion when a high-fat diet is consumed. If the gallbladder is removed, the patient no longer has a high quality and sufficient amount of bile to help him eat a high-fat diet, so his body has to suffer from indigestion, bloating and diarrhea. However, this symptom is often overlooked by surgeons and pushed to the gastroenterology department, becoming a “persistent problem” difficult to treat in internal medicine.