Bone pain inside the breast, generally speaking, the common causes are mainly the following: a. Patients with malignant breast tumors, tumor cells invade the pectoral muscle as well as the rib cage, which can cause stubborn pain in the bone. At this time, ordinary analgesic drugs are not able to relieve patients’ pain symptoms, and patients need to improve mammogram or magnetic resonance examination as soon as possible. After the nature of the lesion is confirmed, mastectomy with lymph node dissection should be performed as soon as possible, and if necessary, the invaded sternum should be removed as well. After surgery, combine with local radiotherapy and systemic chemotherapy to kill the cancer cells in the body and reduce the symptoms of bone pain inside the breast. Second, the patient’s accidental fall during strenuous exercise can cause fracture of the rib inside the breast, which causes severe pain, accompanied by breathing difficulties and restricted activities. Patients can improve the X-ray or CT examination of the ribs to clarify the degree of injury and then perform surgery for internal fixation. Strengthen anti-infection and analgesic treatment to relieve the painful symptoms of breast bone.