Lung cancer with liver metastasis indicates advanced stage, that is, stage IV lung cancer, which may not have a long survival period, most of which is about 0.5-1 year, or more than 1 year or 2 years if the effect is good, but more than 5 years is rare. Lung cancer with liver metastasis can only be considered as local interventional therapy or systemic chemotherapy to control the development of the disease. Genetic testing of the primary lesion of lung cancer can also be done to determine whether targeted drug therapy can be applied. If it is lung adenocarcinoma with positive genetic test and liver metastasis, targeted drug therapy can be considered, such as ERSA, Troche, etc., which may have effects on both primary and metastatic lesions. If treatment with targeted drugs is effective, it can also prolong survival a little, but most patients may hardly exceed 5 years of survival.