Desensitization treatment: 1. What is dust mite? Dust mites are small animals that resemble spiders but are invisible to the naked eye. They live on animal dander and are widely found in bedding, curtains, stuffed toys, air conditioning filters and the air; it is impossible to completely avoid them in life. 2.What is desensitization? Desensitization treatment is a biologic drug made by extracting the active protein in the body of mites, allowing patients to ingest from low to high concentrations, and after 2-3 years of use, the organism develops immune tolerance, so that allergy symptoms can be greatly reduced or even no longer recur. Desensitization is usually divided into subcutaneous injection and sublingual administration. 3. If I receive desensitization treatment, do I still need allopathic medication? At the beginning of the desensitization phase, usually 2-3 months after starting the medication, start with the lowest dose and gradually increase the dose to the maximum. At this stage, the vaccine starts to stimulate the bone marrow to produce antibodies in the body, but the concentration of an IgG4 antibody is low at this time. As the stimulation time of the vaccine increases and the concentration of the vaccine increases, the concentration of IgG4 gradually increases, and reaches the highest concentration 2-3 months after the start of the dose. At the beginning of desensitization, allergic symptoms in the body are not only produced by mites in the environment, but also by the mite vaccine taken orally, therefore, at this stage, more obvious allergic symptoms may be produced, and the concentration of IgG4 in the body is not enough to resist the allergic symptoms produced by mites, therefore, at the beginning of desensitization, anti-allergic treatment is more necessary, generally, at the same time of starting the oral mite vaccine, oral antihistamine such as loratadine is taken every night. The antihistamines such as loratadine should be taken orally every night (for half a month, orally every night at bedtime), and glucocorticoids should be sprayed nasally (for about 2 months or until the maintenance phase of desensitization). 4.When should anti-allergy drugs be used in the maintenance phase of desensitization? Maintenance stage of desensitization At this stage, the IgG4 antibodies in the body have reached the maximum maintenance concentration, and the allergy symptoms can be completely fought by IgG4 antibodies at this time, therefore, no other anti-allergy drugs are generally needed at this stage. Since the concentration of mites in the environment is not constant in most cases, but changes with time and location, while the concentration of IgG4 in the body is always maintained at a high level, therefore, during the maintenance stage of desensitization, if the concentration of mites in the environment is much higher than usual in special environments (such as warehouses, or environments where central air conditioning is used, etc.), or special seasons (spring and autumn, rainy season, etc.) It may induce allergic symptoms in human body for a short period of time, when anti-allergic drugs (loratadine, nasal glucocorticoids) are used for a short period of time. 5.The danger of allergic diseases, why do allergic diseases need desensitization? Allergic diseases are the most common type of chronic diseases. The development of allergic diseases often follows a progressive pattern of deterioration, such as seasonal onset developing into perennial, and the symptoms gradually deteriorating from severe to mild. Desensitization therapy is the only allopathic treatment that can change the natural course of allergic diseases. Early desensitization therapy can significantly reduce or even completely relieve allergic symptoms, gradually reduce or even completely get rid of allopathic medication, and prevent disease aggravation and new allergies. The efficacy can be maintained for a long time after the desensitization treatment is terminated. 6.What are the cost, course of treatment and efficacy of desensitization treatment? The course of desensitization treatment is 2-3 years, and 80% of the patients will have their symptoms relieved within half a year, and if the treatment works in 3-6 months, the whole treatment must be adhered to.