If urticaria occurs at home, patients can immediately take oral antihistamines for relief, like loratadine, cetirizine, paracetamol, and patients can equip themselves with some at home usually. This is because sometimes urticaria attacks can be very urgent, and sometimes they can even cause edema around the mouth and throat directly. If the hives are confined to the skin, topical application of glyburide lotion and glucocorticoid ointment can be used to relieve the hives. Glucocorticoid ointment can consider the application of tretinoin ointment, dexamethasone ointment are available.