Patients using adapalene gel after the peeling stinging may be caused by normal drug effects or drug side effects, normal drug effects caused by the start of a small dose, continue to use the drug, such as the persistence of discomfort or caused by drug side effects, it is recommended to stop using the drug, strengthen the care, or the use of topical ointment to alleviate the symptoms. Adapalene Gel is mainly used for the treatment of acne, papules and pustules, etc. It belongs to the class of retinoids, which can play an anti-inflammatory and anti-epidermal keratinization abnormal effect. Some patients may experience localized skin peeling, stinging, dryness and other side effects when using the drug for 2-4 weeks, but the symptoms are mild and generally do not affect the continuation of treatment. Patients are advised to stop using the drug first and drink plenty of water to replenish the water needed by the body, which can promote metabolism and can help the drug to be excreted from the body as early as possible. For patients with severe side effects causing peeling and tingling, it is recommended that they go to the hospital in time, and can be treated with antihistamines, such as glucocorticoid cream, under the guidance of the doctor, which can alleviate the symptoms of skin allergies. When using Adapalene Gel for the first time, you can apply a small dose to the affected area first, but do not apply it to sunburn, eczema, abrasions, cuts and other wound areas. In case of persistent unrelieved symptoms, it is recommended to temporarily discontinue the medication. Seek medical treatment promptly. It is recommended that the medication should be used as prescribed by the doctor to avoid adverse reactions.