Clinically, many diseases can cause cough, cough yellow sputum, not just a cold cough, cough yellow sputum, such as bronchodilatation, lung abscess, acute exacerbation of chronic obstructive pulmonary disease, pneumonia can be cough, cough yellow sputum, when cough cough, cough yellow sputum symptoms should be actively seeking medical attention, improve the blood routine, C-reactive protein, calcitoninogen, sputum culture, chest X-ray and other related examinations. If the patient is a bacterial infection caused by coughing, coughing yellow sputum, antibiotics need to be used for treatment, commonly used antibiotics include cefixime, amoxicillin, levofloxacin, azithromycin and so on. Sputum culture examination can be improved, according to the results of drug sensitivity test to change antibiotics, if the patient has sputum cough can not be used expectorant drugs, such as ambroxol, eucalyptus pin, acetylcysteine.