With clotrimazole found pregnant may lead to fetal abortion, developmental malformation, or there may be no effect, should be regular obstetric examination. Clotrimazole is mainly used for ringworm, tinea pedis, tinea capitis, tinea cruris, candida onychomycosis and vulvovaginitis and other diseases. In general, pregnant and lactating women need to be used under the guidance of a doctor, except for those who are allergic to Clotrimazole to prohibit the use of the drug, the rest of the contraindications are not clear. In the early stages of pregnancy, especially in the first three months of pregnancy, the fetus is very susceptible to the effects of drugs, usually manifested as direct abortion or no effect. Therefore, the discovery of pregnancy after the use of clotrimazole may have no effect, but may also lead to miscarriage, or developmental malformations, it is recommended to avoid the use of drugs in early pregnancy.