Skin test is not required for imipenem injection. Imipenem belongs to carbapenem antibiotics, which are mainly used clinically for respiratory tract infections, biliary tract infections, urinary tract infections, abdominal infections, and skin, soft tissue, bone, joint, and gynecological infections caused by gram-positive, gram-negative, and anaerobic bacteria. Generally, it should be noted that a few patients will have some adverse reactions with its use, such as allergic phenomena, gastrointestinal reactions, like nausea, vomiting, diarrhea, etc. When using antibiotics like Imipenem, it is best to avoid alcohol, eat lightly, take more rest and drink warm water.